Pifithrin-β hydrobromide

CAS: 511296-88-1

Rif. TM-T3637

Informazioni sul prodotto

• Nome: Pifithrin-β hydrobromide
• Sinonimi: Cyclic PFT-α, PFT-β, Cyclic Pifithrin-α hydrobromide, Pifithrin-β, PFT β (hydrobromide)
• CAS: 511296-88-1

Descrizione

Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM).

• Marchio: Targetmol

Proprietà chimiche

• Peso molecolare: 349.29
• Formula: C₁₆H₁₇BrN₂S
• Purezza: 99.62%
• Colore/Forma: Solid