BLK Protein, Human, Recombinant (His)
Rif. TM-TMPJ-00307
| 1mg | 2.591,00 € | ||
| 10µg | 134,00 € | ||
| 50µg | 391,00 € | ||
| 500µg | 1.803,00 € |
Informazioni sul prodotto
- Tyrosine-Protein Kinase Blk, BLK, B Lymphocyte Kinase, p55-Blk
Tyrosine-Protein Kinase Blk (BLK) contains one protein kinase domain, one SH2 domain and one SH3 domain. BLK is a non-receptor tyrosine kinase, which is involved in B-lymphocyte development, differentiation and signaling. B-cell receptor (BCR) signaling requires a tight regulation of several protein tyrosine kinases and phosphatases, and associated coreceptors. Signaling through BLK plays an important role in transmitting signals through surface immunoglobulines and supports the pro-B to pre-B transition, as well as the signaling for growth arrest and apoptosis downstream of B-cell receptor. Defects in BLK are a cause of maturity-onset diabetes of the young type 11 (MODY11).
Proprietà chimiche
Richiesta tecnica su: TM-TMPJ-00307 BLK Protein, Human, Recombinant (His)
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