Acarbose-1-phenylthiol Dodeca(p-methoxybenzyl Ether)

Rif. TR-A123510

Informazioni sul prodotto

• Nome: Acarbose-1-phenylthiol Dodeca(p-methoxybenzyl Ether)
• Sinonimi: (2R,3R,4S,5R,6R)-6-(((2R,3R,4S,5R,6R)-6-(((2R,3R,4S,5R,6S)-4,5-bis((4-Methoxybenzyl)oxy)-2-(((4-methoxybenzyl)oxy)methyl)-6-(phenylthio)tetrahydro-2H-pyran-3-yl)oxy)-4,5-bis((4-methoxybenzyl)oxy)-2-(((4-methoxybenzyl)oxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)-4,5-bis((4-methoxybenzyl)oxy)-2-methyl-N-((1S,4S,5S,6S)-4,5,6-tris((4-methoxybenzyl)oxy)-3-(((4-methoxybenzyl)oxy)methyl)cyclohex-2-en-1-yl)tetrahydro-2H-pyran-3-amine

Descrizione

Applications Acarbose-1-phenylthiol Dodeca(p-methoxybenzyl Ether) is an intermediate formed in the synthesis of α-D-Glucosyl Acarbose Impurity, a homolog of Acarbose (A123500) for use in the treatment of chronic diseases such as inflammatory (including allergic) diseases, metastatic cancers and infection by pathogenic agents including bacteria, viruses or parasites (1,2,3). Acarbose impurity F.
References (1) Henrissal, B.: Biochem. J., 280, 309 (1991) (2) Qian, M., et al.: J. Mol. Biol., 231, 785 (1993) (3) Brzozowski, A., et al.: Biochemistry, 36, 10837 (1997)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 2179.55
• Formula: C₁₂₇H₁₄₃NO₂₉S
• Colore/Forma: Neat
• SMILES: COc1ccc(COCC2=C[C@H](N[C@H]3C(OCc4ccc(OC)cc4)C(OCc4ccc(OC)cc4)[C@@H](O[C@@H]4C(COCc5ccc(OC)cc5)O[C@H](O[C@@H]5C(COCc6ccc(OC)cc6)O[C@@H](Sc6ccccc6)C(OCc6ccc(OC)cc6)C5OCc5ccc(OC)cc5)C(OCc5ccc(OC)cc5)C4OCc4ccc(OC)cc4)O[C@@H]3C)[C@H](OCc3ccc(OC)cc3)[C@@H](OCc3ccc(OC)cc3)[C@H]2OCc2ccc(OC)cc2)cc1