N-Acetyl-N-[2-(7-methoxy-1-naphthalenyl)ethyl]acetamide

CAS: 1379005-34-1

Rif. TR-A167620

Informazioni sul prodotto

• Nome: N-Acetyl-N-[2-(7-methoxy-1-naphthalenyl)ethyl]acetamide
• Sinonimi: Agomelatine Impurity D

Descrizione

Impurity Agomelatine Diacetyl Impurity / Agomelatine Impurity 7
Applications N-Acetyl-N-[2-(7-methoxy-1-naphthalenyl)ethyl]acetamide is an impurity of Agomelatine (A430000), a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. (Agomelatine Impurity 7)
References Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 285.34
• Formula: C₁₇H₁₉NO₃
• Colore/Forma: White To Off-White
• InChI: InChI=1S/C17H19NO3/c1-12(19)18(13(2)20)10-9-15-6-4-5-14-7-8-16(21-3)11-17(14)15/h4-8,11H,9-10H2,1-3H3
• InChI key: InChIKey=NNGHCTJYAWJHDS-UHFFFAOYSA-N
• SMILES: COc1ccc2cccc(CCN(C(C)=O)C(C)=O)c2c1