AG 14699

CAS: 459868-92-9

Rif. TR-A425500

Informazioni sul prodotto

• Nome: AG 14699
• Sinonimi: AG 014699, Rucaparib, PF-01367338, Ag-14699, AG-014447 (as free base), 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one phosphate, Pf-01367338, Ag-014699, 8-Fluoro-2-[4-(methylaminomethyl)phenyl]-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-6-one phosphate

Descrizione

Applications PARP inhibitor oncolytic.
References Friedman, H., et al.: J. Clin. Oncol., 16, 3851 (1998), Nakajima, H., et al.: J. Pharmacol. Exp. Ther., 312, 472 (2005), Gajewski, T., et al.: Clin. Cancer Res., 11, 7861 (2005),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 421.36
• Formula: C₁₉H₂₁FN₃O₅P
• Colore/Forma: Yellow Solid
• InChI: InChI=1S/C19H18FN3O.H3O4P/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15;1-5(2,3)4/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24);(H3,1,2,3,4)
• InChI key: InChIKey=FCCGJTKEKXUBFZ-UHFFFAOYSA-N
• SMILES: CNCc1ccc(-c2[nH]c3cc(F)cc4c3c2CCNC4=O)cc1.O=P(O)(O)O