Amcinafal

CAS: 3924-70-7

Rif. TR-A576100

Informazioni sul prodotto

• Nome: Amcinafal
• Sinonimi: Triamcinolone 16,17-(3'-Pentanonide), 9-Fluoro-11beta,16alpha,17,21-Tetrahydroxy-, Pregna-1,4-diene-3,20-dione, SQ 15102, (11β,16α)-16,17-[(1-Ethylpropylidene)bis(oxy)]-9-fluoro-11,21-dihydroxypregna-1,4-diene-3,20-dione, (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-8,8-diethyl-4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, (4bR,5S,6bS,9aR,10aS)-8,8-diethyl-4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a-dimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one, 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregna-1,4-diene-3,20-dione deriv., 9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with 3-pentanone, 9alpha-Fluor-11beta,21-dihydroxy-16alpha,17alpha-(methyl)(phenyl)methylendioxy-1,4-pregnadien-3,20-dion, Amcinafal [USAN:INN], Amcinafalum, Amcinafalum [INN-Latin], Ancinafal, Ancinafal [INN-Spanish], Pregna-1,4-diene-3,20-dione, 16,17-[(1-ethylpropylidene)bis(oxy)]-9-fluoro-11,21-dihydroxy-, (11β,16α)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16,17-((1-ethylpropylidene)bis(oxy))-, (11beta,16alpha)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxy-, cyclic 16,17-acetal with 3-pentanone, Sq 15,102, Triamcinolone 16,17-(3′-pentanonide), Unii-68Lrv63Xne

Descrizione

Applications Amcinafal are topical steroidal anti-ainflammitory. Also, it is used in the preparation of Opthalamic composition intended for the treatment of an occular condition in human beings.
References Rabinovich-G., et al.: PCT Int. Appl. (2007), WO 2007138113 A1 20071206

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 462.55
• Formula: C₂₆H₃₅FO₆
• Colore/Forma: Off-White to Pale Yellow Solid
• InChI: InChI=1S/C26H35FO6/c1-5-24(6-2)32-21-12-18-17-8-7-15-11-16(29)9-10-22(15,3)25(17,27)19(30)13-23(18,4)26(21,33-24)20(31)14-28/h9-11,17-19,21,28,30H,5-8,12-14H2,1-4H3/t17-,18-,19-,21+,22-,23-,25-,26+/m0/s1
• InChI key: InChIKey=NSZFBGIRFCHKOE-LFZVSNMSSA-N
• SMILES: CCC1(CC)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1