(S)-2-Amino-N-((S)-1-(4-hydroxyphenyl)-3-oxopropan-2-yl)-3-methylbutanamide

Rif. TR-A611010

Informazioni sul prodotto

• Nome: (S)-2-Amino-N-((S)-1-(4-hydroxyphenyl)-3-oxopropan-2-yl)-3-methylbutanamide
• Sinonimi: Aureusimine A Intermediate

Descrizione

Applications (S)-2-Amino-N-((S)-1-(4-hydroxyphenyl)-3-oxopropan-2-yl)-3-methylbutanamide is an intermediate in the synthesis of Aureusimine A (A794560), a metabolite of non-ribosomal origin produced by Staphylococcus aureusan, formed by the fusion of two amino acids. Aureusimine A was shown to exert control over the virulence cascade responsible for Golden Staph infection.
References Archer, G., et al.: Clin. Infect. Dis., 26, 1179 (1998); Novick, R., et al.: Mol. Microbiol., 48, 1429 (2003); Liang, X., et al.: Infect. Immun., 74, 4655 (2006); Geiger, T., et al.: J. Bacteriol., 190, 3419 (2008);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 302.173
• Formula: C₁₄H₂₀N₂O₃
• Colore/Forma: Off-White Solid
• InChI: InChI=1S/C8H15O10P/c1-16-8(7(11)12)2-4(9)6(10)5(18-8)3-17-19(13,14)15/h4-6,9-10H,2-3H2,1H3,(H,11,12)(H2,13,14,15)/t4?,5?,6-,8-/m1/s1
• InChI key: InChIKey=CCWGGDIDQPGNLT-KIMARDCLSA-N
• SMILES: CO[C@]1(C(=O)O)CC(O)[C@@H](O)C(COP(=O)(O)O)O1