Atorvastatin Lactam Sodium Salt Impurity

CAS: 148217-40-7

Rif. TR-A791775

Informazioni sul prodotto

• Nome: Atorvastatin Lactam Sodium Salt Impurity
• Sinonimi: 1H-Pyrrole-1-heptanoic acid, 5-(4-fluorophenyl)-2,3-dihydro-ß,d-dihydroxy-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-, sodium salt (1:1), (ßR,dR,3R)-, 1H-Pyrrole-1-heptanoic acid, 5-(4-fluorophenyl)-2,3-dihydro-ß,d-dihydroxy-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-, monosodium salt, [3R-[1(ßR*,dR*),3R*]]- (9CI)
• CAS: 148217-40-7

Descrizione

Impurity Atorvastatin Pyrrolidone Analog (USP)
Stability Light Sensitive
Applications A photodegradation product of Atorvastatin (a cyclic impurity of Atorvastatin). Atorvastatin Pyrrolidone Analog (USP).
References Roger, D., et al.: Clin. Exp. Dermatol., 19, 88 (1994), Cosa, G., et al.: Photochem. Photobiol., 80, 159 (2004), Kerwin, B., et al.: J. Pharm. Sci., 96, 1468 (2007),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 596.62
• Formula: C₃₃H₃₄FN₂NaO₆
• Colore/Forma: White
• InChI: InChI=1S/C33H35FN2O6.Na/c1-21(2)33(31(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)30(23-13-15-24(34)16-14-23)36(32(33)42)18-17-26(37)19-27(38)20-28(39)40;/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);/q;+1/p-1/t26-,27-,33-;/m1./s1
• SMILES: CC(C)C1(C(=O)Nc2ccccc2)C(=O)N(CC[C@@H](O)C[C@@H](O)CC(=O)[O-])C(c2ccc(F)cc2)=C1c1ccccc1.[Na+]