(aS,bR)-Bedaquiline

CAS: 843663-66-1

Rif. TR-B119540

Informazioni sul prodotto

• Nome: (aS,bR)-Bedaquiline
• Sinonimi: 3-Quinolineethanol, 6-bromo-a-[2-(dimethylamino)ethyl]-2-methoxy-a-1-naphthalenyl-ß-phenyl-, (aS,ßR)-, (aS,ßR)-6-Bromo-a-[2-(dimethylamino)ethyl]-2-methoxy-a-1-naphthalenyl-ß-phenyl-3-quinolineethanol, Bedaquiline, R 207910, Sirturo, TMC 207, (aS,ßR)-Bedaquiline, (αS,βR)-6-Bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-quinolineethanol, 3-Quinolineethanol, 6-bromo-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-, (αS,βR)-, 6-Bromo-alpha-[2-(dimethylamino)ethyl]-2-methoxy-alpha-1-naphthalenyl-beta-phenyl-3-quinolineethanol, R-207910, Tmc-207
• CAS: 843663-66-1

Descrizione

Applications (aS,bR)-Bedaquiline is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References Cheepsattayakorn, A., et al.: Anti-Infect. Drug. Discover.,7, 141 (2012); de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 555.50
• Formula: C₃₂H₃₁BrN₂O₂
• Colore/Forma: White To Light Yellow
• InChI: InChI=1S/C32H31BrN2O2/c1-35(2)19-18-32(36,28-15-9-13-22-10-7-8-14-26(22)28)30(23-11-5-4-6-12-23)27-21-24-20-25(33)16-17-29(24)34-31(27)37-3/h4-17,20-21,30,36H,18-19H2,1-3H3/t30-,32-/m1/s1