10-Bromo-4-Deoxypodophyllotoxin

CAS: 93108-16-8

Rif. TR-B293800

Informazioni sul prodotto

• Nome: 10-Bromo-4-Deoxypodophyllotoxin
• Sinonimi: (5R,5aR,8aR)-10-Bromo-5-(3,4,5-trimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one

Descrizione

Applications 10-Bromo-4-Deoxypodophyllotoxin is a derivative of 4-Deoxypodophyllotoxin (D249500), a medicinal herb product isolated from Anthriscus sylvestris Hoffm. It is well known for its antitumor, antiviral, and anti-inflammatory activities. 4-Deoxypodophyllotoxin was also shown to inhibit the passive cutaneous anaphylaxis reaction.
References Lin, C.X., et al.: Planta. Med., 70, 474 (2004); Peng, Xu., et al.: Neurotoxicol., 31, 680 (2010); Kim, Y., et al.: Planta, Med., 68, 271 (2002);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 477.3
• Formula: C₂₂H₂₁BrO₇
• InChI: InChI=1S/C22H21BrO7/c1-25-14-5-10(6-15(26-2)20(14)27-3)17-12-7-16-21(30-9-29-16)19(23)13(12)4-11-8-28-22(24)18(11)17/h5-7,11,17-18H,4,8-9H2,1-3H3/t11-,17+,18-/m0/s1
• InChI key: InChIKey=ZDDCTEQZBFBFTM-PDSMFRHLSA-N
• SMILES: COc1cc([C@@H]2c3cc4c(c(Br)c3C[C@H]3COC(=O)[C@@H]32)OCO4)cc(OC)c1OC