2-(Benzyloxy)-3,5-dichlorobenzenecarbaldehyde

CAS: 40359-57-7

Rif. TR-B413888

Informazioni sul prodotto

• Nome: 2-(Benzyloxy)-3,5-dichlorobenzenecarbaldehyde
• Sinonimi: 3,5-Dichloro-2-(phenylmethoxy)benzaldehyde, 2-Benzyloxy-3,5-dichlorobenzaldehyde

Descrizione

Applications 2-(benzyloxy)-3,5-dichlorobenzenecarbaldehyde (cas# 40359-57-7) is an intermediate used in the synthesis of 3'-Hydroxy-4'-methoxydiclofenac (H946710), which is a derivative of Diclofenac (Sodium Salt: D436450). Diclofenac is the first non-steroidal anti-inflammatory drug (NSAID) that is derived from phenylacetic acid. Diclofenac, like other NSAIDs, primarily works by targeting the cyclo-oxygenase pathway in the arachidonic acid cascade, reducing the formation of inflammation mediators in the body.
References Ku, E., et al.: Am. J. Med., 80, 18 (1986); Simmons, D., et al.: Proc. Nat. Acad. Sci., 96, 3275 (1999); Small, R.: Clin. Pharm., 8, 545 (1989)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 281.13
• Formula: C₁₄H₁₀O₂Cl₂
• Colore/Forma: Off-white Solid
• InChI: InChI=1S/C14H10Cl2O2/c15-12-6-11(8-17)14(13(16)7-12)18-9-10-4-2-1-3-5-10/h1-8H,9H2
• InChI key: InChIKey=VTHXNUFLDZNGBA-UHFFFAOYSA-N
• SMILES: O=Cc1cc(Cl)cc(Cl)c1OCc1ccccc1