1-(tert-Butoxycarbonyl)-2-indolinecarboxylic Acid

CAS: 137088-51-8

Rif. TR-B689695

Informazioni sul prodotto

• Nome: 1-(tert-Butoxycarbonyl)-2-indolinecarboxylic Acid
• Sinonimi: 1-Boc-indoline-2-carboxylic Acid, 1-N-Boc-indoline-2-carboxylic Acid, 2,3-Dihydro-indole-1,2-dicarboxylic Acid 1-tert-Butyl Ester, 1-tert-Butyl 2,3-Dihydroindole-1,2-dicarboxylate, (±)-2,3-Dihydro-1H-indole-1,2-dicarboxylic Acid 1-(1,1-Dimethylethyl) Ester, Indoline-2-carboxylic acid, N-BOC protected

Descrizione

Applications 1-(tert-Butoxycarbonyl)-2-indolinecarboxylic Acid is used to prepare benzopyranyl indoline analogs as cardioselective anti-ischemic ATP-sensitive potassium channel openers. It is also used in the synthesis of 1,2,3,4-tetrahydroisoquinoline derivatives as potent and selective M2 muscarinic receptor antagonists.
References Lee, S., et al.: Eur. J. Med. Chem., 38, 459 (2003); Watanabe, T., et al.: Chem. Phama. Bull., 47, 672 (1999)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 263.29
• Formula: C₁₄H₁₇NO₄
• InChI: InChI=1S/C14H17NO4/c1-14(2,3)19-13(18)15-10-7-5-4-6-9(10)8-11(15)12(16)17/h4-7,11H,8H2,1-3H3,(H,16,17)
• InChI key: InChIKey=QONNUMLEACJFME-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)N1c2ccccc2CC1C(=O)O