tert-Butyl ((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)carbamate

CAS: 247068-81-1

Rif. TR-B809468

Informazioni sul prodotto

• Nome: tert-Butyl ((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)carbamate
• Sinonimi: (S)-4-(tert-Butoxycarbonylamino)-2,6-dimethyl-1-hepten-3-one, tert-Butyl ((4S)-2,6-dimethyl-3-oxohept-1-en-4-yl)carbamate

Descrizione

Applications tert-Butyl ((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)carbamate is an intermediate in the synthesis of (S)-2-Amino-4-methyl-1-((S)-2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt which is an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 255.35
• Formula: C₁₄H₂₅NO₃
• Colore/Forma: Solid
• InChI: InChI=1S/C14H25NO3/c1-9(2)8-11(12(16)10(3)4)15-13(17)18-14(5,6)7/h9,11H,3,8H2,1-2,4-7H3,(H,15,17)/t11-/m0/s1
• InChI key: InChIKey=VCNCNAPAHSSWCI-UHFFFAOYSA-N
• SMILES: Oc1c(Br)ccc(Br)c1Br