4,5'-Bis-[N,N-di-(carboxymethyl)-aminomethyl]-fluorescein (Acetoxymethyl) Ester
CAS: 890090-35-4
Rif. TR-C125400
1mg | 454,00 € | ||
5mg | 1.670,00 € | ||
500µg | 252,00 € |
Informazioni sul prodotto
- N,N'-[[3',6'-Bis(acetyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-diyl]bis(methylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1'-Bis[(acetyloxy) methyl] Ester
- Calcein Acetoxymethyl Ester
- NSC 689290
Applications Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein (sc-202090), which is an extremely fluorescent and negatively charged molecule. Calcein-AM can be used to stain living cells and in cytoplasmic Schwann cells has been observed to fluoresce bright green. Calcein-AM has been reported to be a neutral substrate for P-glycoprotein (Pgp) and multidrug resistance protein (MRP) and has been used in flow cytometry studies to analyze the function of P-gp and MRP.
References Feller, N., et al.: Br. J. Cancer, 72, 543 (1995); Dhar, S., et al.: Eur. J. Pharmacol., 346, 315 (1998); Essodaigui, M., et al.: Biochemistry, 37, 2243 (1998); Lemasters, J.J., et al.: Biochim. Biophys. Acta., 1366,177 (1998);
Proprietà chimiche
Richiesta tecnica su: TR-C125400 4,5'-Bis-[N,N-di-(carboxymethyl)-aminomethyl]-fluorescein (Acetoxymethyl) Ester
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