1-Carboxy-3-adamantanol

CAS: 42711-75-1

Rif. TR-C177735

Informazioni sul prodotto

• Nome: 1-Carboxy-3-adamantanol
• Sinonimi: 3-Hydroxy-tricyclo[3.3.1.13,7]decane-1-carboxylic Acid, 3-Hydroxy-1-adamantanecarboxylic Acid, 3-Carboxy-1-hydroxyadamantane, 3-Hydroxy-1-adamantanecarboxylic Acid, 3-Hydroxy--1-Amantane Carboxylic Acid, 3-Hydroxy-1-adamantanecarboxylic acid, 3-Hydroxy-1-Adamantane Carboxylic Acid, (5R,7R)-3-hydroxytricyclo[3.3.1.1~3,7~]decane-1-carboxylate, 3-Hydroxytricyclo[3.3.1.1~3,7~]Decane-1-Carboxylic Acid

Descrizione

Applications 1-Carboxy-3-adamantanol is used in the synthesis of potent pyridyl amide/sulfonamide inhibitors of 11β-HSD-1 which could be applied to a treatment of ulcers or in hormone therapy treatments relating to cortisol.
References Agarwal, A. et al.: Endocr. Res., 29, 411 (2004); Wang, H. et al.: Bioorg. Med. Chem. Lett., 21, 4146 (20110;

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 196.24
• Formula: C₁₁H₁₆O₃
• Colore/Forma: Off-White Solid
• InChI: InChI=1S/C11H16O3/c12-9(13)10-2-7-1-8(3-10)5-11(14,4-7)6-10/h7-8,14H,1-6H2,(H,12,13)
• InChI key: InChIKey=CJJMAWPEZKYJAP-UHFFFAOYSA-N
• SMILES: O=C(O)C12CC3CC(CC(O)(C3)C1)C2