(2Z)​-7-​Chloro-​2-​[[[(1S)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-​2-​heptenoic Acid

CAS: 877674-77-6

Rif. TR-C368515

Informazioni sul prodotto

• Nome: (2Z)​-7-​Chloro-​2-​[[[(1S)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-​2-​heptenoic Acid
• Sinonimi: (2Z)-7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid, (Z)-(S)-7-chloro-2-(2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid, 2-Heptenoic acid, 7-chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-, (2Z)-, 7-Chloro-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-2-heptenoic acid, Cdcha

Descrizione

Stability Hygroscopic
Applications (2Z)​-7-​Chloro-​2-​[[[(1S)​-​2,​2-​dimethylcyclopropyl]​carbonyl]​amino]​-​2-​heptenoic Acid is a reagent used in the preparation of Cilastatin (C441105), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 273.76
• Formula: C₁₃H₂₀ClNO₃
• Colore/Forma: Neat
• InChI: InChI=1S/C13H20ClNO3/c1-13(2)8-9(13)11(16)15-10(12(17)18)6-4-3-5-7-14/h6,9H,3-5,7-8H2,1-2H3,(H,15,16)(H,17,18)/b10-6-/t9-/m1/s1
• InChI key: InChIKey=OTSSACCOAAGLRY-WPVMNKCKSA-N
• SMILES: CC1(C)C[C@@H]1C(=O)N/C(=C\CCCCCl)C(=O)O