3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene

CAS: 23964-56-9

Rif. TR-C380873

Informazioni sul prodotto

• Nome: 3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene
• Sinonimi: Methyl 3-(2-chloropropanoylamino)-4-methyl-2-thiophenecarboxylate

Descrizione

Applications 3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene is an intermediate in the synthesis of Articaine-d7 Hydrochloride which is the labelled form of Articaine Hydrochloride (A777905). Articaine Hydrochloride is the Hydrochloride Salt of Articaine (A777900). Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry.
References Malamed, S.F., et al.: J. Am. Dent. Assoc., 132, 177 (2001); Luan, F., et al.: Bioorg. Med. Chem., 21, 1870 (2013)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 261.73
• Formula: C₁₀H₁₂ClNO₃S
• Colore/Forma: Neat
• InChI: InChI=1S/C10H12ClNO3S/c1-5-4-16-8(10(14)15-3)7(5)12-9(13)6(2)11/h4,6H,1-3H3,(H,12,13)
• InChI key: InChIKey=DDOQBQRIEWHWBT-UHFFFAOYSA-N
• SMILES: NC(CCP(=O)(O)O)C(=O)O