5-Cyclopropyl-10-(1-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol

CAS: 156458-93-4

Rif. TR-C417355

Informazioni sul prodotto

• Nome: 5-Cyclopropyl-10-(1-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol
• Sinonimi: 2-cyclopropyl-9-piperidin-1-yltricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,9,12,14-heptaen-2-ol, 5H-Dibenzo[a,d]cyclohepten-5-ol, 5-cyclopropyl-10-(1-piperidinyl)-, (±)-, 5H-Dibenzo[a,d]cyclohepten-5-ol, 5-cyclopropyl-10-(1-piperidinyl)-

Descrizione

Applications 5-Cyclopropyl-10-(1-piperidinyl)-5H-dibenzo[a,d]cyclohepten-5-ol is an intermediate in the synthesis of 10-Hydroxy (E)-Amitriptyline (D462790). (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 331.451
• Formula: C₂₃H₂₅NO
• Colore/Forma: Neat
• InChI: InChI=1S/C23H25NO/c25-23(18-12-13-18)20-10-4-2-8-17(20)16-22(24-14-6-1-7-15-24)19-9-3-5-11-21(19)23/h2-5,8-11,16,18,25H,1,6-7,12-15H2
• InChI key: InChIKey=UPLBRZUWLDDXKY-UHFFFAOYSA-N
• SMILES: OC1(C2CC2)c2ccccc2C=C(N2CCCCC2)c2ccccc21