Clemastine N-Oxide

CAS: 108825-05-4

Rif. TR-C568505

Informazioni sul prodotto

• Nome: Clemastine N-Oxide
• Sinonimi: Pyrrolidine, 2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-, 1-oxide, [R-(R*,R*)]- (9CI), (1RS,2R)-2-[2-[(1R)-1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine 1-Oxide, [R-(R*,R*)]- 2-[2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine 1-Oxide, Clemastine EP Impurity A, (1RS,2R)-2-[2-[(1R)-1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine 1-Oxide

Descrizione

Impurity Clemastine EP Impurity A
Applications Clemastine N-Oxide (Clemastine EP Impurity A) is a metabolite of Clemastine Fumarate (C568500); a H1 histamine receptor antagonist and antihistaminic.
References Froehlich, L., et al.: Pharmazie, 51, 409 (1996); Weidmann, et al.: Boll. Chim. Farm., 106, 467 (1967); Gober, B., et al.: Pharmazie, 43, 539 (1988); Breccia, A., et al.: Curr. Ther. Res., 49, 622 (1991); Schran, H., et al.: J. Clin. Pharmacol., 36, 911 (1996)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 359.89
• Formula: C₂₁H₂₆ClNO₂
• Colore/Forma: Light Yellow
• InChI: InChI=1S/C21H26ClNO2/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)25-16-14-20-9-6-15-23(20,2)24/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3/t20-,21-,23?/m1/s1
• InChI key: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#Cc1cc(/C=C2/OC(=O)c3ccccc32)ccc1F