2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide

CAS: 24522-30-3

Rif. TR-C982245

Informazioni sul prodotto

• Nome: 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide
• Sinonimi: Leflunomide Imp. H (EP), Teriflunomide impurity B, Leflunomide Impurity H, Teriflunomide Impurity B, p-Acetotoluidide, 2-cyano-α,α,α-trifluoro-, p-Acetotoluidide,2-cyano-a,a,a-trifluoro- (8CI)
• CAS: 24522-30-3

Descrizione

Impurity Leflunomide EP Impurity H
Stability Hygroscopic
Applications 2-Cyano-N-[4-(trifluoromethyl)phenyl]acetamide (Leflunomide EP Impurity H) is used to prepare aminothiophene carboxylates and carboxamides as adenosine A1 receptor allosteric enhancers. It is also used to synthesize (1,2,3-triazol-4-yl)benzenamines as inhibitors against VEGF receptors 1 and 2.
References Nikolakopoulos, G., et al.: Bioorg. Med. Chem., 14, 2358 (2006); Kiselyov, A., et al.: Bioorg. Med. Chem. Lett., 19, 1344 (2009)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 228.17
• Formula: C₁₀H₇F₃N₂O
• Colore/Forma: White to Off-White Solid
• InChI: InChI=1S/C10H7F3N2O/c11-10(12,13)7-1-3-8(4-2-7)15-9(16)5-6-14/h1-4H,5H2,(H,15,16)
• SMILES: N#CCC(=O)Nc1ccc(C(F)(F)F)cc1