Cyclic 17-(1,2-Ethanediyl Acetal) Androst-4-ene-3,17-dione

CAS: 1044-89-9

Rif. TR-C990020

Informazioni sul prodotto

• Nome: Cyclic 17-(1,2-Ethanediyl Acetal) Androst-4-ene-3,17-dione
• Sinonimi: 17,17-(Ethylenedioxy)androst-4-en-3-one

Descrizione

Applications Cyclic 17-(1,2-Ethanediyl Acetal) Androst-4-ene-3,17-dione is an intermediate in the synthesis of Dehydroepiandrosterone-d5 which is the labeled analogue of Dehydro Epiandrosterone (D229585). Dehydro Epiandrosterone is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.
References Yahara, M., et al.: J. Toxicol. Sci., 2, 161 (1977), Morales, A.J., et al.: J. Clin. Endocrinol. Metab., 78, 1360 (1994), Ebeling, P., et al.: Lancet, 343, 1479 (1994),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 330.46
• Formula: C₂₁H₃₀O₃
• Colore/Forma: Neat
• InChI: InChI=1S/C21H30O3/c1-19-8-5-15(22)13-14(19)3-4-16-17(19)6-9-20(2)18(16)7-10-21(20)23-11-12-24-21/h13,16-18H,3-12H2,1-2H3/t16-,17+,18+,19+,20+/m1/s1
• InChI key: InChIKey=UOXYIRLWWGUICN-FTCYEJDNSA-N
• SMILES: CN[C@H](C(=O)OCC(CO)OCn1cnc2c(=O)[nH]c(N)nc21)C(C)C.Cl