Deacetylvinblastine Hydrazide

CAS: 55383-37-4

Rif. TR-D199065

Informazioni sul prodotto

• Nome: Deacetylvinblastine Hydrazide
• Sinonimi: 4-Desacetylvinblastine 3-carbohydrazide, 4-Desacetylvinblastine 3-carboxyhydrazide 4-Desacetylvincaleukoblastine 3-carboxyhydrazide, Desacetylvinblastine hydrazide, 2H-3,7-Methanoazacycloundecino[5,4-b]indole, vincaleukoblastin-23-oic acid deriv., Vincaleukoblastin-23-oic acid, O4-deacetyl-, hydrazide, 1H-Indolizino[8,1-cd]carbazole, vincaleukoblastin-23-oic acid deriv., Deacetylvinblastine hydrazide

Descrizione

Applications Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent that is currently under development as an anti-cancer agent.
References Pribble, P. & Edelman, M.: Expert Opin. Invest. Drugs, 21, 755 (2012); Reddy, J., et al.: Cancer Res., 67, 4434 (2007); Roy, M., et al.:

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 768.94
• Formula: C₄₃H₅₆N₆O₇
• Colore/Forma: Neat
• InChI: InChI=1S/C43H56N6O7/c1-6-39(53)21-25-22-42(38(52)56-5,33-27(13-17-48(23-25)24-39)26-11-8-9-12-30(26)45-33)29-19-28-31(20-32(29)55-4)47(3)35-41(28)15-18-49-16-10-14-40(7-2,34(41)49)36(50)43(35,54)37(51)46-44/h8-12,14,19-20,25,34-36,45,50,53-54H,6-7,13,15-18,21-24,44H2,1-5H3,(H,46,51)/t25-,34-,35+,36+,39-,40+,41+,42-,43-/m0/s1
• InChI key: InChIKey=DTPBJHCTIBQLMO-UHFFFAOYSA-N
• SMILES: Cc1cc(=O)oc2cc(OC3OC(CO)C(OC4OC(CO)C(OC5OC(CO)C(O)C(O)C5O)C(O)C4O)C(O)C3O)ccc12