6-Dehydrocortisol

CAS: 600-99-7

Rif. TR-D229145

Informazioni sul prodotto

• Nome: 6-Dehydrocortisol
• Sinonimi: Hydrocortisone Imp. E (EP),1-[[4-[2-[(3,5-Di-chloro-2-methoxybenzoyl)amino]ethyl]phenyl]sulfonyl]-3-cyclohexylurea, Glibenclamide Imp. E (Pharmeuropa), 11beta,17,21-Trihydroxypregna-4,6-diene-3,20-dione, Delta6-Hydrocortisone, Pregna-4,6-diene-3,20-dione, 11,17,21-trihydroxy-, (11beta)- (9CI), Pregna-4,6-diene-3,20-dione, 11beta,17,21-trihydroxy- (8CI), NSC 12881, Delta6-Cortisol, Hydrocortisone Impurity E
• CAS: 600-99-7

Descrizione

Impurity Hydrocortisone EP Impurity E
Applications 6-Dehydrocortisol (Hydrocortisone EP Impurity E) is a metabolite of Cortisol (H714615), a glucocorticoid, produced by the zona fasciculata of the adrenal gland. 6-Dehydrocortisol was used in the identification of Trp-371 as the main site of specific photoaffinity labeling of corticosteroid binding globulin.
References Grenot, C., et al.: Biochem., 33, 8969 (1994); Justice, J.B., et al.: J. Med. Chem., 21, 465 (1978); Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 360.44
• Formula: C₂₁H₂₈O₅
• Colore/Forma: Light Yellow
• InChI: InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h3-4,9,14-16,18,22,24,26H,5-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• InChI key: InChIKey=IFOXVSBZLASBJM-VWUMJDOOSA-N
• SMILES: C[C@]12C[C@H](O)[C@H]3[C@@H](C=CC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO