O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine

CAS: 113994-45-9

Rif. TR-D289480

Informazioni sul prodotto

• Nome: O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine
• Sinonimi: 2-[(carboxymethoxy)methyl]-4-(2-chlorophenyl)-6-methyl- 3-ethyl 5-methyl Ester 3,5-pyridinedicarboxylic Acid, 2-([4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-2-pyridyl]methoxy)acetic Acid
• CAS: 113994-45-9

Descrizione

Applications O-Des[2-aminoethyl]-O-carboxymethyl-dehydroamlodipine is the metablolite of Amlodipine (A633495), a long-acting calcium channel blocker that is commonly used as an anti-hypertensive in the treatment of cardiovascular conditions.
References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986), Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987), Haria, M., et al.: Drugs, 50, 560 (1995),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 421.83
• Formula: C₂₀H₂₀ClNO₇
• Colore/Forma: Neat
• InChI: InChI=1S/C20H20ClNO7/c1-4-29-20(26)18-14(9-28-10-15(23)24)22-11(2)16(19(25)27-3)17(18)12-7-5-6-8-13(12)21/h5-8H,4,9-10H2,1-3H3,(H,23,24)
• InChI key: InChIKey=WYLSEDHKQJBUIA-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1c(COCC(=O)O)nc(C)c(C(=O)OC)c1-c1ccccc1Cl