O-Desmethyl N-Methyl Lacosamide

Rif. TR-D294770

Informazioni sul prodotto

• Nome: O-Desmethyl N-Methyl Lacosamide
• Sinonimi: (R)-2-Acetamido-N-benzyl-3-hydroxy-N-methylpropanamide

Descrizione

Applications O-Desmethyl N-Methyl Lacosamide is an intermediate in the synthesis of N-Methyl Lacosamide (M315210), which is the methyl analogue of Lacosamide (L098500), a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.
References Lees, G., et al.: Brain Res., 612, 190 (1993), Kuo, C., et al.: Mol. Pharmacol., 51, 1077 (1997); Barton, M., et al.: Epilepsy Res., 47, 217 (2001); Beyreuther, B., et al.: Eur. J. Pharmacol., 539, 64 (2006); Beyreuther, B., et al.: CNS Drug Rev., 13, 21 (2007)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 250.29
• Formula: C₁₃H₁₈N₂O₃
• Colore/Forma: Neat
• InChI: InChI=1S/C13H18N2O3/c1-10(17)14-12(9-16)13(18)15(2)8-11-6-4-3-5-7-11/h3-7,12,16H,8-9H2,1-2H3,(H,14,17)/t12-/m1/s1
• SMILES: CNc1cc([N+](=O)[O-])ccc1N