(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate

CAS: 376608-71-8

Rif. TR-D446035

Informazioni sul prodotto

• Nome: (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
• Sinonimi: Benzeneacetic acid, a-hydroxy-, (aR)-(1R,2S)-compd. with 2-(3,4-difluorophenyl)cyclopropanamine (1:1), Benzeneacetic acid, a-hydroxy-, (aR)-, compd. with (1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine (1:1) (9CI), (1R,2S)-2-(3,4-Difluorophenyl)cyclopropan-1-amine (R)-mandelate, (1R,2S)-2-(3,4-Difluoro phenyl)cyclopropanaminium (2R)-hydroxy(phenyl) ethanoate, (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (R)-2-hydroxy-2-phenylacetate, (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanaminium (2R)-hydroxy(phenyl)ethanoate, (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine, (1R,2S)-2-(3,4-difluorophenyl)cyclopropan-1-amine (R)-2-hydroxy-2-phenylacetate, (2R)-2-hydroxy-2-phenylacetic acid, (2R,3R)-2,3-Bis((4-Methylbenzoyl)Oxy)Butanedioic Acid Compd.With(3R,4R)-N,4-Dimethyl-1-(Phenylmethyl)-3-Piperidinamine, (aR)-a-hydroxy-benzeneacetic acid compd. with (1R,2S)-2-(3,4-difluorophenyl) cyclopropanamine (1:1), Benzeneacetic acid, (2R)-hydroxy-, (R)-(1R,2S)-compd. with 2-(3,4-difluorophenyl)cyclopropanamine (1:1), Benzeneacetic acid, α-hydroxy-, (αR)-(1R,2S)-compd. with 2-(3,4-difluorophenyl)cyclopropanamine (1:1), Benzeneacetic acid, α-hydroxy-, (αR)-, compd. with (1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine (1:1)
• CAS: 376608-71-8

Descrizione

Applications (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate in the preparation of orally active reversible P2Y12 receptor antagonists such as Ticagrelor (T437700)for the prevention of thrombosis.
References Springthorpe, B. et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 321.32
• Formula: C₁₇H₁₇F₂NO₃
• Colore/Forma: Neat
• InChI: InChI=1S/C9H9F2N.C8H8O3/c10-7-2-1-5(3-8(7)11)6-4-9(6)12;9-7(8(10)11)6-4-2-1-3-5-6/h1-3,6,9H,4,12H2;1-5,7,9H,(H,10,11)/t6-,9+;7-/m01/s1
• InChI key: InChIKey=XKAABIQBASHVGG-JYBVLTNNSA-N
• SMILES: N[C@@H]1C[C@H]1c1ccc(F)c(F)c1.O=C(O)C(=O)O.c1ccccc1