2-((8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-hydroxyacetic Acid

Rif. TR-D452650

Informazioni sul prodotto

• Nome: 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-hydroxyacetic Acid

Descrizione

Applications 2-((8S,9S,10R,11S,13S,14S,17R)-11,17-Dihydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-hydroxyacetic Acid is an alternative form of 20-Dihydro Hydrocortisone 21-Carboxylic Acid (D452415), which is a new class of corticosteroids synthesized on the basis of the antedrug concept, possess local anti-inflammatory activity without systemic toxicties.
References Lee, H.J., et al.: Drugs. Under. Exp. Clin. Res., 10, 835 (1984); Lee, H.J., et al.: J. Steroid. Biochem., 14, 1325 (1981);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 378.46
• Formula: C₂₁H₃₀O₆
• Colore/Forma: White to Off-White Solid
• InChI: InChI=1S/C21H30O6/c1-19-7-5-12(22)9-11(19)3-4-13-14-6-8-21(27,17(24)18(25)26)20(14,2)10-15(23)16(13)19/h9,13-17,23-24,27H,3-8,10H2,1-2H3,(H,25,26)/t13-,14-,15-,16+,17?,19-,20-,21-/m0/s1
• InChI key: InChIKey=KZENJDWRIKLICU-PEIJZJCNSA-N
• SMILES: C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@]2(O)C(O)C(=O)O