Informazioni sul prodotto
Nome:
7,8-Dihydroxyflavone
Sinonimi:
- 7,8-Dihydroxy-2-phenyl-4H-chromen-4-one
- 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
- 4H-1-Benzopyran-4-one, 7,8-dihydroxy-2-phenyl-
- 7,8-Dihydroxy-2-phenyl-4-benzopyrone
- 7,8-Dihydroxy-flavone
- 7,8-dihydroxy-2-phenyl-4H-chromen-4-one
- Brn 0234350
- Flavone, 7,8-dihydroxy-
Descrizione:
Applications 7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD. It has recently been shown to counteract the inhibition of NMDA receptor caused by lead poisoning and confer protective effects in live rats.
References Devi, L. et al.: Neuropsychopharmacology, 37, 434 (2012); Andero, R. et al.: Hippocampus, 22, 399 (2012); Johnson, R.A. et al.: J. Appl. Physiol., 112, 704 (2012); Chem. and Eng. News Nov. 20, 2017, page 5
Avviso:
I nostri prodotti sono destinati esclusivamente ad uso di laboratorio. Per qualsiasi altro utilizzo, vi preghiamo di contattarci.
Marchio:
TRC
Conservazione lunga:
Note:
Proprietà chimiche
Peso molecolare:
254.24
Formula:
C15H10O4
Colore/Forma:
Pale Yellow to Yellow Solid
InChI:
InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H
InChI key:
InChIKey=COCYGNDCWFKTMF-UHFFFAOYSA-N
SMILES:
O=c1cc(-c2ccccc2)oc2c(O)c(O)ccc12
MDL:
Punto di fusione:
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