25-Des(dimethylbutenyl) 25-(1,3-Dimethyl-2,3-epoxybutnyl) Moxidectin (>85%)

Rif. TR-D589238

Informazioni sul prodotto

• Nome: 25-Des(dimethylbutenyl) 25-(1,3-Dimethyl-2,3-epoxybutnyl) Moxidectin (>85%)
• Sinonimi: (1R,4S,4'E,5'S,6R,6'S,8R,10E,13R,14E,16Z,20R,21S,24S)-21,24-dihydroxy-4'-methoxyimino-5',11,13,22-tetramethyl-6'-[(2R)-2-methyl-3-propan-2-yloxiran-2-yl]spiro[3,7,18-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one

Descrizione

Applications 25-Des(dimethylbutenyl) 25-(1,3-Dimethyl-2,3-epoxybutnyl) Moxidectin is a by-product during the synthesis of 3,4-Epoxy-moxidectin (E589045), which is derived from the parent compound Moxidectin (M744800), a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.Also, it is one of the impurities of Moxidectin under stress conditions.
References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005); Awasthi, A., et al.: Anal. Bioanal. Chem., 404, 2203-2222 (2012)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 655.818
• Formula: C₃₇H₅₃NO₉
• Purezza: >85%
• Colore/Forma: Off-White To Light Yellow
• InChI: InChI=1S/C37H53NO9/c1-20(2)32-35(7,46-32)33-24(6)29(38-42-8)18-36(47-33)17-26-16-25(45-36)13-12-22(4)14-21(3)10-9-11-30-37(41)27(34(40)44-26)15-23(5)31(39)28(37)19-43-30/h9-12,15,20-21,24-28,31-33,39,41H,13-14,16-19H2,1-8H3/b10-9+,22-12+,30-11-,38-29+/t21-,24-,25+,26-,27-,28+,31+,32?,33-,35+,36-,37+/m0/s1
• InChI key: InChIKey=SCFHZTXWGKMPPJ-OPWPZVGUSA-N
• SMILES: CO/N=C1\C[C@]2(C[C@@H]3C[C@@H](C/C=C(\C)C[C@@H](C)/C=C/C=C4\OC[C@@H]5[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)O[C@H]([C@]2(C)OC2C(C)C)[C@H]1C