Efaproxiral

CAS: 131179-95-8

Rif. TR-E415000

Informazioni sul prodotto

• Nome: Efaproxiral
• Sinonimi: Propanoic acid, 2-[4-[2-[(3,5-dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methyl-, 2-[4-[2-[(3,5-Dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methylpropanoic acid, 2-[4-[(3,5-Dimethylanilino carbonyl)methyl]phenoxy]-2-methylpropionic acid, 2-[4-[[[(3,5-Dimethylphenyl)amino]carbonyl]methyl]phenoxy]-2-methylpropionic acid, RSR 13, 2-(4-(((3,5-Dimethylanilino)Carbonyl)Methyl)Phenoxy)-2-Methylpropionic Acid, 2-(4-{2-[(3,5-Dimethylphenyl)Amino]-2-Oxoethyl}Phenoxy)-2-Methylpropanoic Acid, 2-[4-(3,5-Dimethylphenylcarbamoylmethyl)phenoxy]-2-methylpropionic acid, Propanoic acid, 2-[4-[2-[(3,5-dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methyl-, Rsr 13
• CAS: 131179-95-8

Descrizione

Applications Allosteric modifier of hemoglobin (HB). Binds in the central water cavity of the Hb molecule causing a conformational change such that bound oxygen is released more readily. Antineoplastic adjunct (radiosensitizer).
References Abraham, D.J., et al.: Biochemistry, 31, 9141 (1992), Pagel, P.S., et al.: J. Pharmacol. Exp. Ther., 285, 1 (1998), Kleinberg, L., et al.: J. Clin. Oncol., 17, 2593 (1999),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 341.40
• Formula: C₂₀H₂₃NO₄
• Colore/Forma: Neat
• InChI: InChI=1S/C20H23NO4/c1-13-9-14(2)11-16(10-13)21-18(22)12-15-5-7-17(8-6-15)25-20(3,4)19(23)24/h5-11H,12H2,1-4H3,(H,21,22)(H,23,24)
• InChI key: InChIKey=BNFRJXLZYUTIII-UHFFFAOYSA-N
• SMILES: Cc1cc(C)cc(NC(=O)Cc2ccc(OC(C)(C)C(=O)O)cc2)c1