Erlotinib-3-vinyl Hydrochloride

CAS: 1624294-38-7

Rif. TR-E625005

Informazioni sul prodotto

• Nome: Erlotinib-3-vinyl Hydrochloride
• Sinonimi: 6,7-Bis(2-methoxyethoxy)-N-(3-vinylphenyl)quinazolin-4-amine Hydrochloride, N-(3-Ethenylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Hydrochloride (1:1)

Descrizione

Stability Light and Air sensitive
Applications Erlotinib-3-vinyl Hydrochloride is an impurity of is an impurity of Erlotinib Hydrochloride (E625000), a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Antineoplastic.
References Moyer, J.D., et al.: Cancer Res., 57, 4838 (1997); Hidalgo, M., et al.: J. Clin. Oncol., 19, 3267 (2001); Perez-Soler, R., et al.: J. Clin. Oncol., 22, 3238 (2004); Blackhall, F.H., et al.: Expert Opin. Pharmacother., 6, 995 (2005)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 431.91
• Formula: C₂₂H₂₆ClN₃O₄
• Colore/Forma: Off-White Solid
• InChI: InChI=1S/C22H25N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h4-7,12-15H,1,8-11H2,2-3H3,(H,23,24,25);1H
• InChI key: InChIKey=PVYZSHZFBOSTSM-UHFFFAOYSA-N
• SMILES: C=Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1.Cl