(S)-N-((3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)-N-methylacetamide

Rif. TR-F532260

Informazioni sul prodotto

• Nome: (S)-N-((3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)-N-methylacetamide
• Sinonimi: (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)-N-methylacetamide

Descrizione

Applications (S)-N-((3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)-N-methylacetamide is a Linezolid (L466500) impurity. Linezolid is a prototype of the oxazolidinone antimicrobials; inhibits bacterial mRNA translation.
References Brickner, S.J., et al.: J. Med. Chem., 39, 673 (1996), Ford, C.W., et al.: Antimicrob. Agents Chemother., 40, 1508 (1996), Rybak, M.J., et al.: Pharmacotherapy, 18, 456 (1998), Stevens, D.L., et al.: Clin. Infect. Dis., 34, 1481 (2002),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 351.37
• Formula: C₁₇H₂₂FN₃O₄
• Colore/Forma: Neat
• InChI: InChI=1S/C17H22FN3O4/c1-12(22)19(2)10-14-11-21(17(23)25-14)13-3-4-16(15(18)9-13)20-5-7-24-8-6-20/h3-4,9,14H,5-8,10-11H2,1-2H3/t14-/m0/s1
• InChI key: InChIKey=ZDZAYMWZGCJPFX-AWEZNQCLSA-N
• SMILES: CC(=O)N(C)C[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1