Forskolin Hemisuccinate

CAS: 83797-56-2

Rif. TR-F701805

Informazioni sul prodotto

• Nome: Forskolin Hemisuccinate
• Sinonimi: 1-[(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-Ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-5-yl] Ester Butanedioic Acid, 1H-Naphtho[2,1-b]pyran, Butanedioic Acid Deriv.
• CAS: 83797-56-2

Descrizione

Applications Forskolin Hemisuccinate is a derivative fo Forskolin (F701800), a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin Hemisuccinate was found to inhibit E-selectin gene transcription through a cAMP-dependent protein kinase pathway.
References Chersa, P., et al.: J. Biol. Chem., 269, 29129 (1994); Mende, T.J., et al.: Tetrahedron Lett., 31, 5307 (1990); Gupta, P.P., et al.: Indian. J. Pharmacol., 26, 150 (1994);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 468.54
• Formula: C₂₄H₃₆O₉
• Colore/Forma: Off White Solid
• InChI: InChI=1S/C24H36O9/c1-7-21(4)12-14(26)24(31)22(5)13(25)10-11-20(2,3)18(22)17(30)19(23(24,6)33-21)32-16(29)9-8-15(27)28/h7,13,17-19,25,30-31H,1,8-12H2,2-6H3,(H,27,28)/t13-,17-,18-,19-,21-,22-,23+,24-/m0/s1