GSK 690693 Hydrochloride

CAS: 1029067-05-7

Rif. TR-G797725

Informazioni sul prodotto

• Nome: GSK 690693 Hydrochloride
• Sinonimi: 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-Butyn-2-ol

Descrizione

Applications GSK 690693 Hydrochloride is an ATP-competitive pan-Akt kinase inhibitor. Also plays a role in the inhibition of other members of the AGC family of kinases which prevents the phosphorylation of downstream Akt substrates resulting in the induction of apoptosis in human tumor cells. Anti-proliferative agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rhodes, N. et al.: Canc. Res., 68, 2366 (2008);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 426.457
• Formula: C₂₁H₂₈ClN₇O₃
• Colore/Forma: Pale Yellow Solid
• InChI: InChI=1S/C21H30O9/c1-11-6-7-12(2)13(10-11)28-9-5-8-21(3,4)20(27)30-19-16(24)14(22)15(23)17(29-19)18(25)26/h6-7,10,14-17,19,22-24H,5,8-9H2,1-4H3,(H,25,26)/t14?,15-,16?,17?,19+/m1/s1
• InChI key: InChIKey=CJMNXSKEVNPQOK-DLIURNGASA-N
• SMILES: Cc1ccc(C)c(OCCCC(C)(C)C(=O)O[C@@H]2OC(C(=O)O)[C@H](O)C(O)C2O)c1