(R)-Hydroperoxy Des(boric Acid) Bortezomib

CAS: 886979-78-8

Rif. TR-H715415

Informazioni sul prodotto

• Nome: (R)-Hydroperoxy Des(boric Acid) Bortezomib
• Sinonimi: 2-Pyrazinecarboxamide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, Pyrazinecarboxamide, N-[(1S)-2-[[(1S)-1-hydroperoxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]- (9CI), Bortezomib S-hydroperoxide (USP)

Descrizione

Impurity Bortezomib USP Impurity L
Stability Unstable in Methanol
Applications (R)-Hydroperoxy Des(boric Acid) Bortezomib is an impurity of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 372.42
• Formula: C₁₉H₂₄N₄O₄
• Colore/Forma: White To Off-White
• InChI: InChI=1S/C19H24N4O4/c1-13(2)10-17(27-26)23-18(24)15(11-14-6-4-3-5-7-14)22-19(25)16-12-20-8-9-21-16/h3-9,12-13,15,17,26H,10-11H2,1-2H3,(H,22,25)(H,23,24)/t15-,17-/m0/s1
• InChI key: InChIKey=ATPZUYZYORUVIK-RDJZCZTQSA-N
• SMILES: CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)OO