2-Hydroxypropyl Nortadalafil (Mixture of Diastereomers)

CAS: 1353020-85-5

Rif. TR-H952705

Informazioni sul prodotto

• Nome: 2-Hydroxypropyl Nortadalafil (Mixture of Diastereomers)
• Sinonimi: Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(2-hydroxypropyl)-, (6R,12aR)-, (6R,12aR)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(2-hydroxypropyl)pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 2-Hydroxypropylnortadalafil, 2-Hydroxypropyl Nortadalafil
• CAS: 1353020-85-5

Descrizione

Applications 2-Hydroxypropyl Nortadalafil is a derivative of Tadalafil (T004500), which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.
References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005), Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005), Toomey, V. et al.: J. Pharm. Biomed. Anal., 59, 50 (2012);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 433.46
• Formula: C₂₄H₂₃N₃O₅
• Colore/Forma: Neat
• InChI: InChI=1S/C24H23N3O5/c1-13(28)10-26-11-21(29)27-18(24(26)30)9-16-15-4-2-3-5-17(15)25-22(16)23(27)14-6-7-19-20(8-14)32-12-31-19/h2-8,13,18,23,25,28H,9-12H2,1H3/t13?,18-,23-/m1/s1
• InChI key: InChIKey=YGRCGCUDAOLEEX-LWQTYFCDSA-N
• SMILES: CC(O)CN1CC(=O)N2[C@@H](c3ccc4c(c3)OCO4)c3[nH]c4ccccc4c3C[C@@H]2C1=O