(E)-5-[2-(5-Nitro-2-furyl)vinyl]-2-furoic Acid
CAS: 18873-34-2
Rif. TR-N182660
5mg | Fuori produzione | ||
10mg | Fuori produzione | ||
50mg | Fuori produzione |
Informazioni sul prodotto
Applications (E)-5-[2-(5-Nitro-2-furyl)vinyl]-2-furoic Acid is an intermediate in the synthesis of 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester (N493870), which is an inhibitor of G protein-coupled receptor kinase 2. 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester (N493870) was shown to normalize vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction.
References Taguchi, K., et al.: Endocrinol., 153, 2985 (2012);