Nafarelin Acetate

CAS: 76932-60-0

Rif. TR-N190010

Informazioni sul prodotto

• Nome: Nafarelin Acetate
• Sinonimi: 6-[3-(2-Naphthalenyl)-D-alanine]-luteinizing Hormone-releasing Factor (pig) Acetate Salt, Nafareline Acetate, [6-D-(2-naphthyl)-alanine]LH-RH Acetate
• CAS: 76932-60-0

Descrizione

Applications Nafarelin Acetate is a gonadotropin-releasing hormone agonist. Treatment with Nafarelin improves sleep disturbances and anxiety-depression. Nafarelin is also used in the treatment of estrogen-dependent gynecologic disorders such as endometriosis and uterine leiomyomas.
References Simberg, N., et al.: Acta. Obstet. Gyn. Scan., 77, 854 (1998); Bergqvist, A., et al.: Acta. Obstet. Gyn. Scan., 80, 628 (2001); Tahara, M., et al.: Fertil. Steril., 73, 799 (2000)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 1322.47+x(60.05)
• Formula: C₆₆H₈₃N₁₇O₁₃•xC₂H₄O₂
• Colore/Forma: Neat
• InChI: InChI=1S/C66H83N17O13.C2H4O2/c1-36(2)25-48(58(89)76-47(13-7-23-71-66(68)69)65(96)83-24-8-14-54(83)64(95)73-33-55(67)86)77-60(91)50(28-38-15-18-39-9-3-4-10-40(39)26-38)78-59(90)49(27-37-16-19-43(85)20-17-37)79-63(94)53(34-84)82-61(92)51(29-41-31-72-45-12-6-5-11-44(41)45)80-62(93)52(30-42-32-70-35-74-42)81-57(88)46-21-22-56(87)75-46;1-2(3)4/h3-6,9-12,15-20,26,31-32,35-36,46-54,72,84-85H,7-8,13-14,21-25,27-30,33-34H2,1-2H3,(H2,67,86)(H,70,74)(H,73,95)(H,75,87)(H,76,89)(H,77,91)(H,78,90)(H,79,94)(H,80,93)(H,81,88)(H,82,92)(H4,68,69,71);1H3,(H,3,4)/t46-,47-,48-,49-,50+,51-,52-,53-,54-;/m0./s1
• InChI key: InChIKey=GUJYDLHACHDKAJ-CFWZQLQRSA-N
• SMILES: CC(=O)O.CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O