Prostratin

CAS: 60857-08-1

Rif. TR-P838800

Informazioni sul prodotto

• Nome: Prostratin
• Sinonimi: (1aR,1bS,4aR,7aS,7bR,8R,9aS)-9a-(Acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a, (1aR,1bS,4aR,7aS,7bR,8R,9aS)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl acetate, (1bS,4aR)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl acetate, (1bS,4aR,7aS,7bR,8R)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl acetate, 12-Deoxyphorbol 13-acetate, 13-O-Acetyl-12-deoxyphorbol, 5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 9a-(acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-, (1aR,1bS,4aR,7aS,7bR,8R,9aS)-, 5H-Cyclopropa[3,4]benz[1,2-e]azulen-5-one, 9a-(acetyloxy)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-, [1aR-(1aα,1bβ,4aβ,7aα,7bα,8α,9aα)]-, K 101A, NSC 623310, Sa 101A, Stillingia factor S₇
• CAS: 60857-08-1

Descrizione

Applications It is a protein kinase C activator found in the bark of the mamala tree of Samoa, Homalanthus nutans (Euphorbiaceae). Research indicated that prostratin has potential to be useful in the treatment of HIV as it flushes viral reservoirs in latently infected CD4+ T-cells.
References Reuben, et al.: Clin. Cancer Res., 6, 1671 (2000), Korin, Y., et al.: J. Virol., 76, 8118 (2002), Wei, X., et al.: Nature, 422, 307 (2003), Kutsch, O., et al.: Antimicrob. Agents Chemother., 48, 1652 (2004),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 390.47
• Formula: C₂₂H₃₀O₆
• Colore/Forma: Neat
• InChI: InChI=1S/C22H30O6/c1-11-6-16-20(26,18(11)25)9-14(10-23)7-15-17-19(4,5)21(17,28-13(3)24)8-12(2)22(15,16)27/h6-7,12,15-17,23,26-27H,8-10H2,1-5H3/t12-,15+,16-,17-,20-,21+,22-/m1/s1
• InChI key: InChIKey=YHPLKWQJMAYFCN-UHFFFAOYSA-N
• SMILES: NCCCNCCS