Prucalopride Succinate

CAS: 179474-85-2

Rif. TR-P838950

Informazioni sul prodotto

• Nome: Prucalopride Succinate
• Sinonimi: Butanedioic acid, compd. with 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-7-benzofurancarboxamide (1:1), 7-Benzofurancarboxamide, 4-amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidinyl]-, butanedioate (1:1) (9CI), R 108512, Resolor, Resotran, Prucalopride INTERMEDIATES, Prucalopride succinate
• CAS: 179474-85-2

Descrizione

Applications Prucalopride is a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.
References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 485.96
• Formula: C₁₈H₂₆N₃O₃Cl•CH₆O₄
• Colore/Forma: Neat
• InChI: 5-3(6)1-2-4(7)8/h11-12H,2-10,20H2,1H3,(H,21,23), 1-2H2,(H,5,6)(H,7,8), InChI=1S/C18H26ClN3O3.C4H6O4/c1-24-9-2-6-22-7-3-12(4-8-22)21-18(23)14-11-15(19)16(20)13-5-10-25-17(13)14
• InChI key: InChIKey=QZRSNVSQLGRAID-UHFFFAOYSA-N
• SMILES: COCCCN1CCC(NC(=O)c2cc(Cl)c(N)c3c2OCC3)CC1.O=C(O)CCC(=O)O