3-(3-Pyridinylcarbonyl-D4)-1-(trimethylsilyl)-2-pyrrolidinone
CAS: 53844-42-1
Rif. TR-P991922
25mg | 283,00 € | ||
50mg | 500,00 € | ||
250mg | 1.748,00 € |
Informazioni sul prodotto
- 3-(2,4,5,6-tetradeuteriopyridine-3-carbonyl)-1-trimethylsilylpyrrolidin-2-one
Applications 3-(3-Pyridinylcarbonyl-D4)-1-(trimethylsilyl)-2-pyrrolidinone is an intermediate in the synthesis of (S)-(-)-Nicotine-d4 (N412452). Labelled analogue of (S)-(-)-Nicotine, a prototype nicotinic acetylcholine receptor agonist. (S)-(-)-Nicotine is the naturally occurring isomer. Nicotine can be absorbed through the alimentary canal, respiratory tract and intact skin. Nicotine is used in the treatment of smoking withdrawal syndrome. Nicotine has been used as an anthelmintic.
References Geffken, D. et al.: Am. J. Epidemiol., 153, 242 (2001); Bolego, C. et al.: Cardiovasc. Res., 53, 568 (2002); Leone, A. et al.: Curr. Pharm. Des., 1, 2199 (2005);
Proprietà chimiche
Richiesta tecnica su: TR-P991922 3-(3-Pyridinylcarbonyl-D4)-1-(trimethylsilyl)-2-pyrrolidinone
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