3b,5a-Tetrahydronorethisterone

CAS: 6424-05-1

Rif. TR-T294140

Informazioni sul prodotto

• Nome: 3b,5a-Tetrahydronorethisterone
• Sinonimi: 19-Nor-5α,17α-pregn-20-yne-3β,17-diol (6CI,7CI,8CI), 17α-Ethynyl-5α-estrane-3β,17β-diol, 17α-Ethynyl-5α-oestrane-3β,17β-diol, 19-Norpregn-20-yne-3,17-diol, (3β,5α,17α)-, 5alpha-Estran-17alpha-ethinyl-3beta,17beta-diol

Descrizione

Applications A 3β-metabolite of progesterone receptor agonist Norethindrone (N676000) that acts as a estrogen receptor agonist in osteoblastic cells. It also has novel nongenomic endothelium-independent vasorelaxing effects.
References Lemus, A.E. et al.: J. Endocrinol., 200, 199 (2009); Perusquia, M. et al.: Eur. J. Pharmacol., 475, 161 (2003); Blom, M.J. et al.: Drug Metab. Disp., 29, 976 (2001);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 302.451
• Formula: C₂₀H₃₀O₂
• Colore/Forma: White to Off-White Solid
• InChI: InChI=1S/C20H30O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,13-18,21-22H,4-12H2,2H3/t13-,14-,15-,16+,17+,18-,19-,20-/m0/s1
• SMILES: C#C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@@H]4[C@H]3CC[C@@]21C