(1R,3S,5S,8aS)-Tetrahydro-5-phenyl-1,3-dipropyl-3H,8H-oxazolo[4,3-c][1,4]oxazin-8-one

CAS: 208932-18-7

Rif. TR-T295745

Informazioni sul prodotto

• Nome: (1R,3S,5S,8aS)-Tetrahydro-5-phenyl-1,3-dipropyl-3H,8H-oxazolo[4,3-c][1,4]oxazin-8-one
• Sinonimi: (1R,3S,5S,8aS)-5-phenyl-1,3-dipropyl-3,5,6,8a-tetrahydro-1H-[1,3]oxazolo[4,3-c][1,4]oxazin-8-one

Descrizione

Applications (1R,3S,5S,8aS)-Tetrahydro-5-phenyl-1,3-dipropyl-3H,8H-oxazolo[4,3-c][1,4]oxazin-8-one is an intermediate used in the synthesis of (2S,3R)-3-Hydroxynorleucine (H949760), which is an analogue of DL-6-Hydroxy Norleucine (H948855), an intermediate for antiviral and antihypertensive drugs.
References Kaufman, S., et al.: J. Biol. Chem., 257, 14667 (1982), Hanson, R., et al.: Bioorg. Chem., 18, 116 (1990), Oshima, T., et al.: J. Bacteriol., 173, 3943 (1991), Oshima, T., et al.: Eur. J. Biochem., 222, 305 (1994), Robl, J., et al.: J. Med. Chem., 40, 1570 (1997)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 303.396
• Formula: C₁₈H₂₅NO₃
• Colore/Forma: Neat
• InChI: InChI=1S/C18H25NO3/c1-3-8-15-17-18(20)21-12-14(13-10-6-5-7-11-13)19(17)16(22-15)9-4-2/h5-7,10-11,14-17H,3-4,8-9,12H2,1-2H3/t14-,15-,16+,17+/m1/s1
• InChI key: InChIKey=KLKVGLLJYXCJLR-NCOADZHNSA-N
• SMILES: CCC[C@@H]1O[C@H](CCC)[C@H]2C(=O)OC[C@H](c3ccccc3)N12