Tetraisopropyl Methylenediphosphonate

CAS: 1660-95-3

Rif. TR-T296270

Informazioni sul prodotto

• Nome: Tetraisopropyl Methylenediphosphonate
• Sinonimi: Medronic Acid Imp. B (EP), P,P'-Methylenebisphosphonic acid, Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester (9CI), Phosphonic acid, methylenedi-, tetraisopropyl ester (7CI,8CI), Methylenediphosphonic acid tetraisopropyl ester, NSC 226577, Tetraisopropyl methylenebisphosphonate, Tetrakis(O-isopropyl) methylenediphosphonate, [(Diisopropoxyphosphinyl)methyl]diisopropoxyphosphine oxide, Medronic Acid Impurity B, 2-[Di(propan-2-yloxy)phosphorylmethyl-propan-2-yloxyphosphoryl]oxypropane, Phosphonic acid, P,P'-methylenebis-, P,P,P',P'-tetrakis(1-methylethyl) ester, Phosphonic acid, methylenebis-, tetrakis(1-methylethyl) ester, Phosphonic acid, methylenedi-, tetraisopropyl ester, Tetraisopropylmethylenediphosphonate, Tetrapropan-2-Yl Methanediylbis(Phosphonate)
• CAS: 1660-95-3

Descrizione

Applications Tetraisopropyl Methylenediphosphonate is used in the preparation of E2-bisphosphonate conjugates as potential anti-osteoporosis agents. Also used in the preparation of AZT 5’-Triphosphate compounds which display inhibitory effects on HIV-1 reverse transcrpitase.
References Wang, G. et al.: J. Med. Chem., 47, 6902 (2004); Gil, L. et al.: Bioorg. Med. Chem., 7, 901 (1999);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 344.32
• Formula: C₁₃H₃₀O₆P₂
• Colore/Forma: Neat
• InChI: InChI=1S/C13H30O6P2/c1-10(2)16-20(14,17-11(3)4)9-21(15,18-12(5)6)19-13(7)8/h10-13H,9H2,1-8H3
• InChI key: InChIKey=ODTQUKVFOLFLIQ-UHFFFAOYSA-N
• SMILES: CC(C)OP(=O)(CP(=O)(OC(C)C)OC(C)C)OC(C)C