Thyroxine (100% pure T4 reference standard (free of T3))

CAS: 51-48-9

Rif. TR-T425650

Informazioni sul prodotto

• Nome: Thyroxine (100% pure T4 reference standard (free of T3))
• Sinonimi: Thyroxine, L- (8CI), (-)-Thyroxine, 3,3',5,5'-Tetraiodo-L-thyronine, Henning, L-T4, L-Thyroxin, L-Thyroxine, Levothyroxine, Levotiron, NSC 36397, SK&F 1-6528, T4, T4 (hormone), THX, Tetraiodothyronine, Thyrax, Thyreoideum, Thyroxin, Thyroxinal, Thyroxine, L-Tyrosine
• Marchio: TRC

Descrizione

Applications Thyroxine is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.
References Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976); Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988); Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996); Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997);

Proprietà chimiche

• Peso molecolare: 776.87
• Formula: C₁₅H₁₁I₄NO₄
• Colore/Forma: Neat
• InChI: InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1
• InChI key: InChIKey=XUIIKFGFIJCVMT-LBPRGKRZSA-N
• SMILES: N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)O