(3S)-1-Tosyl-alpha,alpha-diphenyl-3-pyrrolidineacetonitrile

CAS: 133099-09-9

Rif. TR-T662005

Informazioni sul prodotto

• Nome: (3S)-1-Tosyl-alpha,alpha-diphenyl-3-pyrrolidineacetonitrile
• Sinonimi: (S)-2,2-Diphenyl-2-(1-tosyl-3-pyrrolidinyl)acetonitrile, 2,2-Diphenyl-2-((3S)-1-tosyl-3-pyrrolidinyl)acetonitrile, (S)-2,2-Diphenyl-2-(1-tosylpyrrolidin-3-yl)acetonitrile,(S)-1-[(4-Methylphenyl)sulfonyl]-α,α-diphenyl-3-pyrrolidineacetonitrile, (3S)-1-[(4-Methylphenyl)sulfonyl]-α,α-diphenyl-3-pyrrolidineacetonitrile, (3S)-1-[(4-methylphenyl)sulfonyl]-diphenyl-3-Pyrrolidineacetonitrile, (S)-2,2-Diphenyl-2-(1-Tosylpyrrolidin-3-Yl)Acetonitrile, (S)-3-(1-Cyano-1,1-Diphenylmethyl)-1-Tosyloxy Pyrrolidine, (S)-3-(1-Cyano-1,1-Diphenylmethyl)-1-Tosyloxypyrrolidine, (s)-3-(1-cyano-1,1-diphenylmethyl)-1-tosyloxypyrrolidine (Darifenacin), 2-[(3S)-1-(4-Methylphenyl)sulfonylpyrrolidin-3-yl]-2,2-diphenylacetonitrile, 3-(S)-(+)-(1-cyano-1,1-diphenylmethyl)-1-tosylpyrrolidine, 3-Pyrrolidineacetonitrile, 1-[(4-methylphenyl)sulfonyl]-α,α-diphenyl-, (3S)-, 3-Pyrrolidineacetonitrile, 1-[(4-methylphenyl)sulfonyl]-α,α-diphenyl-, (S)-, {(3S)-1-[(4-methylphenyl)sulfonyl]pyrrolidin-3-yl}(diphenyl)acetonitrile
• CAS: 133099-09-9

Descrizione

Applications (3S)-1-Tosyl-α,α-diphenyl-3-pyrrolidineacetonitrile is a reactant used in the preparation of Darifenacin Hydrobromide (D193400), which is used as a medication to treat urinary incontinence. It works by blocking the M3 muscarinic acetylcholine receptor.
References Murthy, M.V., et. al.: J. Pharm. Biomed. Anal., 72, 40 (2013); Beaumont, K.C., et al.: Xenobiotica, 28, 63 (1998); Chapple, C.R., et al.: Expert Opin. Invest. Drugs, 13, 1493 (2004); Haab, F., et al.: Eur. Urol., 45, 420 (2004)

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 416.54
• Formula: C₂₅H₂₄N₂O₂S
• Colore/Forma: White Solid
• InChI: InChI=1S/C25H24N2O2S/c1-20-12-14-24(15-13-20)30(28,29)27-17-16-23(18-27)25(19-26,21-8-4-2-5-9-21)22-10-6-3-7-11-22/h2-15,23H,16-18H2,1H3/t23-/m1/s1
• InChI key: InChIKey=MWYIBGSOAYLDRH-UHFFFAOYSA-N
• SMILES: CCOC(=O)COc1cc(NS(=O)(=O)c2ccc(C)cc2)c2nc(C=C(C)C)ccc2c1