XAV 939

CAS: 284028-89-3

Rif. TR-X744000

Informazioni sul prodotto

• Nome: XAV 939
• Sinonimi: NVP-XAV 939
• CAS: 284028-89-3

Descrizione

Applications A tankyrase (TNKS) inhibitor that antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. XAV 939 inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Huang, S. et al.: Nature, 461, 614 (2009); Wang, H. et al.: ACS Chem. Biol., 6, 192 (2011); Adles, M.E. et al.: Sci. Signal., 91, ec326 (2009);

• Marchio: TRC

Proprietà chimiche

• Peso molecolare: 312.31
• Formula: C₁₄H₁₁F₃N₂OS
• Colore/Forma: White to Pale Yellow Solid
• InChI: InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
• InChI key: InChIKey=KLGQSVMIPOVQAX-UHFFFAOYSA-N
• SMILES: O=c1nc(-c2ccc(C(F)(F)F)cc2)[nH]c2c1CSCC2