CymitQuimica ha oltre 25 partner, tra i quali spicca il fornitore TargetMol

Endonuclease IV is an apurinic/apyrimidinic (AP) endonuclease that functions as a DNA repair enzyme. It exhibits endonuclease activity at AP sites, possesses 3' phosphodiesterase activity (allowing it to remove various blocking lesions at the 3' end of DNA), and demonstrates endonuclease activity against oxidative DNA damage, as well as 3' to 5' exonuclease activity.

E.coli tRNA adenosine deaminase is derived from Escherichia coli and functions as an adenosine deaminase. It effectively deaminates adenine within single-stranded RNA (ssRNA, primarily in the loop regions of tRNA) or double-stranded RNA (dsRNA) but lacks deaminase activity on DNA. This enzyme is a protein-engineered mutant form of adenosine deaminase, efficiently deaminating adenine in ssDNA, making it useful for adenine base editing (ABE) and RNA m6A methylation sequencing.

C2 Protein (human) is a naturally glycosylated peptide with a 20-amino acid signal sequence. It plays a critical regulatory role in the early activation stages of the classical pathway and is involved in the formation of the classical pathway C3 convertase, C4b2a.

C1qProtein (Rat) is a subunit of the complement system. It can recognize various ligands and plays a role in maintaining immune system balance, promoting tissue repair, and defending against pathogens.

T5 Exonuclease is a DNA exonuclease that exhibits 5′-3′ exonuclease activity on both single-stranded and double-stranded DNA. It also possesses single-strand endonuclease and 5′-flap endonuclease activity.

Elastase (high purity) is a serine protease that hydrolyzes proteins and peptides.

C3 Protein (human) is an intrinsically glycosylated polypeptide composed of two disulfide-linked chains. Complement protein C3 is a pivotal molecule within the complement system, and its activation is fundamental to all essential functions of this system.

T4endonucleaseVII exhibits broad substrate specificity, enabling it to bind and cleave both DNA duplexes and single-base mismatches in three- and four-way branched DNA structures.

Neuron-specific enolase, Human (EC 4.2.1.11), is an enolase enzyme that serves as a biomarker for traumatic brain injury (TBI), stroke following cardiac arrest, hypoxic encephalopathy, and acute spinal cord injury (SCI).

<p>Manganese chloride tetrahydrate) is a high-purity manganese salt that can serve as a cofactor for enzyme reactions and provide essential trace elements</p>

<p>Heptanoic acid sodium is the sodium salt of Heptanoate. can inhibit the osteoporosis and gluconeogenesis of Heptanoate.</p>

<p>2-Amino-2-methyl-1,3-propanediol is an activator of 2-oxoaldehyde dehydrogenase a solid-solid phase change material (PCM) and biological buffer.</p>

<p>2-Amino-2-methyl-1-propanol (AMP) is an emulsifier, pH buffer, and surfactant used to prepare solutions with a pH of 8.7–10.4, P falciparum.</p>

<p>MOPSO sodium is an amphoteric ionic biological buffer with an effective pH range of 6.2 to 7.6, commonly used in cell culture,</p>

<p>Magnesium Sulfate Heptahydrate is a biochemical reagent suitable for cell culture, which can be added to culture media to support microbial growth.</p>

Copper Sulfate Pentahydrate has a variety of antibacterial activities, S aureus, E coli, Pseudomonas aeruginosa, Candida albicans, etc.

<p>Copper(Ⅱ) Sulfate (Cupric sulfate) antibacterial,Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Plasmodium falciparum, etc.</p>

<p>Potassium bromide is a biochemical reagent that can be used as a sedative or in combination with phenobarbital as an anticonvulsant drug</p>

<p>Iron(II) sulfate heptahydrate is an important iron salt commonly used in water treatment as a flocculant, as well as a fertiliser and soil conditioner</p>

<p>Silver chloride can be used as a buffer in electrodes or spectroscopic analysis. inhibitory activity against various bacteria and antitumour activity</p>

<p>Sodium 2-oxobutanoate is an organic compound commonly used as an acidity regulator, leavening agent, and preservative.</p>

Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a metal chelator that binds with divalent and trivalent metal cations, including calcium. It exhibits antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemic, and anticoagulant properties. EDTA sodium hydrate reduces protein oxidation damage catalyzed by metal ions and maintains a reducing environment during protein purification, making it a common choice for protein purification and storage. Additionally, it can alleviate liver fibrosis and is used in research related to coronary artery disease and neurological disorders.

<p>Sodium acetate trihydrate is a phase-change energy storage material that releases heat when forming crystals. prepare buffer solutions with a pH of 3.6-5.6</p>

<p>Ammonium trifluoroacetate is commonly used to prepare buffer solutions with a pH of 5.0-6.5, maintaining a stable pH environment.</p>

<p>Sodium 1-heptanesulfonate monohydrate is a reagent used in ion-pair chromatography for analysing biomolecules such as peptides and proteins.</p>

<p>Magnesium Chloride Hexahydrate is a cofactor required for DNA polymerase activity and plays a key role in PCR processes</p>

<p>Tetrasodium pyrophosphate has inhibitory activity against CA1 and CA2 and a chelating agent, emulsifier and buffer.</p>

<p>Sodium phosphate dibasic heptahydrate is commonly used to prepare PBS buffer solutions with a pH of 7.4, maintaining a stable pH environment</p>

<p>Copper(II) acetate is a high-purity copper reagent that can serve as a copper source in inorganic synthesis</p>

<p>Potassium Ferrocyanide Trihydrate is a stable coordination compound and oxidising agent, used for solution preparation in cell biology and enzyme experiments.</p>

<p>Sodium tripolyphosphate can chelate metal ions and is commonly used as a detergent additive and water softener.buffer pH of 9.2–10.5.</p>

Tri-Potassium Phosphate Monohydrate is a reagent widely used in biochemical experiments, preparing buffer solutions and preventing hypophosphatemia.

<p>Sodium thiosulfate can be used as a substrate for thiosulfate sulfurtransferase and as a reducing agent and standard solution for iodometric titration.</p>

<p>Molybdic acid is used in the preparation of molybdenum compounds and catalysts</p>

<p>Ammonium Molybdate Tetrahydrate,quantitative or qualitative detection of phosphates,a molybdenum source in fertiliser additives, a negative stain.</p>

<p>Zeylanine is a useful organic compound for research related to life sciences and the catalog number is TSP-21001062.</p>

Ancistrocladine is a natural product and has a wide range of applications in life science related research.

Clerodin is a useful organic compound for research related to life sciences and the catalog number is TSP-21087008.

Clausenidin is a useful organic compound for research related to life sciences and the catalog number is TSP-21087020.

Surangin B is a natural product and has a wide range of applications in life science related research.

Dihydroatisine is a useful organic compound for research related to life sciences and the catalog number is TSP-21212004.

Acrovestone is a useful organic compound for research related to life sciences and the catalog number is TSP-21212019.

Kopsine is a natural product and has a wide range of applications in life science related research.

3-epi Caryoptin is a useful organic compound for research related to life sciences and the catalog number is TSP-40962761.

<p>Podoblastin A (D-mannitol) is a useful organic compound for research related to life sciences and the catalog number is TSP-41077145.</p>

Ajaconine is a useful organic compound for research related to life sciences and the catalog number is TSP-41507048.

alpha-Desmotroposantonin is a useful organic compound for research related to life sciences and the catalog number is TSP-41868968.

Humulone is a natural product and has a wide range of applications in life science related research.

Clausantalene is a useful organic compound for research related to life sciences and the catalog number is TSP-43417379.

Uridine diphosphate glucuronic acid (UDP-GlcA) trisodium is a cofactor formed by the catalytic activity of UDP-glucose dehydrogenase. It contains an Azide group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules that have Alkyne groups. Additionally, it can participate in strain-promoted azide-alkyne cycloaddition reactions (SPAAC) with molecules containing DBCO or BCN groups.

<p>DEPC-Treated Water is a RNase-free ultra-pure water that prevents contamination by non-specific nucleases and exonucleases, leaving RNase activity unaffected.</p>

Lipopolysaccharides from *Salmonella enterica* serotype Abortusequi are endotoxins and TLR-4 activators derived from intestinal S. enterica. They are mutated R-type LPSs that serve as pathogen-associated molecular patterns (PAMP) to activate the immune system and induce cell secretion of exosomes. These lipopolysaccharides consist of a core oligosaccharide and lipid A. *S. enterica* serotype Abortusequi is a key pathogen causing abortion in mares and is associated with neonatal septicemia, multiple abscesses, orchitis, and polyarthritis in equine species. Grouping is primarily based on lipopolysaccharide (O-antigen) and flagellin protein (H-antigen).

LNA-UTP is a nucleotide analogue used in the synthesis of oligonucleotides.

<p>2'-F-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>

2′-O-MOE-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.

UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.

<p>2'-F-UMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>

<p>2′-OMe-ADP is a nucleotide analogue used in oligonucleotide synthesis.</p>

<p>Dmf-dg (2'-Deoxy-N2-dimethylaminomethylene-guanosine) is a nucleoside of deoxyguanosine (dG) with a dimethylaminomethylene (DMF) base protection, employed in the synthesis of oligonucleotides.</p>

<p>7-Methylguanosine 5′-monophosphate (7-Methylguanylic acid) is a component of nucleic acids.</p>

<p>2′-OMe-GDP is a nucleotide analog utilized for the synthesis of oligonucleotides.</p>

<p>LNA-CTP is a nucleotide analog utilized in the synthesis of oligonucleotides.</p>

<p>2-Amino-2'-fluoro-2'-deoxyadenosine is a component of nucleic acids.</p>

2'-F-CDP is a nucleotide analog that can be utilized in the synthesis of oligonucleotides.

2′-F-UDP is a nucleotide analogue used in the synthesis of oligonucleotides.

2'-O-MOE-UTP is a nucleotide analog employed in the synthesis of oligonucleotides.

<p>2′-O-MOE-CMP is a nucleotide analogue utilized in the synthesis of oligonucleotides.</p>

<p>LNA-GDP is a nucleotide analog utilized in the synthesis of oligonucleotides.</p>

<p>Pseudouridine5'-OTBDPS [5-(5-O-TBDPS-β-D-ribofuranosyl)uracil] is an intermediate of Pseudouridine.</p>

LNA-AMP is a nucleotide analog used in the synthesis of oligonucleotides.

LNA-GMP, a nucleotide analogue, is utilized in the synthesis of oligonucleotides.

<p>2'-O-MOE-GMP is a nucleotide analogue that can be utilized in the synthesis of oligonucleotides.</p>

<p>2'-Deoxycytidine (Deoxycytidine) hydrate is a component of nucleic acids.</p>

<p>LNA-GTP is a nucleotide analog used in the synthesis of oligonucleotides.</p>

2'-O-MOE-GTP is a nucleotide analog utilized in the synthesis of oligonucleotides.

<p>HSV-60mer sodium is a 60 bp double-stranded oligonucleotide that includes viral DNA motifs from the herpes simplex virus 1 (HSV-1) genome. Transfection of HSV-60mer effectively induces IFN-β in a manner dependent on STING, TBK1, and IFN regulatory factor 3 (IRF3).</p>

<p>dsVACV-70mer sodium is a 70 base pair double-stranded oligonucleotide that contains a viral DNA motif derived from vaccinia virus DNA. It effectively induces IFN-β through a STING-dependent mechanism.</p>

ISD (interferon stimulatory DNA) Control sodium is a non-immunostimulatory single-stranded oligonucleotide with a sequence identical to its double-stranded counterpart, ISD.

2′-OMe-UDP is a nucleotide analog utilized in the synthesis of oligonucleotides.

Morpholino U subunit is one of the fundamental components of morpholino oligonucleotides, capable of pairing with adenine in target RNA.

3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite serves as a precursor of adenosine nucleotide monomers used in the solid-phase synthesis of oligonucleotides, particularly for modifying oligonucleotides such as terminally modified DNA strands. It features Trityl (Tr), Cyanoethyl (CE), and Dimethylformamidine (DMF) protective groups, classifying it as a ddNTP adenosine nucleoside suitable for applications like oligonucleotide solid-phase synthesis, probe design, and chain termination sequencing.

3'-NH2-CTP is a nucleotide analog modified with an amino group at the 3' position of CTP.

5'-DMT-3'-CE-2'-TBDMS cyanoethoxycarbonyl-cytidine is a nucleotide analog used in nucleic acid synthesis.

5'-O-DMTr-2'-O-TBDMS-5-Me-U-3'-CE Phosphoramidite is a nucleoside phosphoramidite monomer modified with protective groups, suitable for RNA oligonucleotide synthesis.

3′-Amino-2′,3′-dideoxy-CTP is an analog of nucleoside triphosphates. It selectively inhibits DNA polymerase β.

2'-Amino-2'-deoxyadenosine-5'-O-diphosphate (2'-NH2-ADP) sodium is an amine-modified nucleotide, serving as a structural analog of the purine nucleotide ADP.

3'-NH-Tr-2',3'-ddG(iBu)-5'-CE-Phosphoramidite is a nucleoside phosphoramidite monomer featuring protective group modifications, suitable for RNA oligonucleotide synthesis.

3'-Bromo ANT-dGTP [3'-O-(5-Bromoanthraniloyl)-2'-deoxyguanosine-5'-O-triphosphate] sodium is a derivative of dGTP.

Sp-dUTPαS tetrasodium is an isomer of the sulfur-containing nucleotide dUTPαS.

Sodium taurocholate hydrate, a cholesterol breakdown product, cycles from bile to liver, changing forms via microbes and enzymes.

N,N-Bis(2-hydroxyethyl)-p-phenylenediamine is an intermediate compound.

Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) is a triacylglycerol found in dietary fats and a type of endogenous metabolite.

<p>Thymine: Derived from DNA hydrolysis or methylcyanoacetylurea, found in DNA (not RNA), binds adenine, used in biochemical research.</p>

<p>2-Adamantanol (2-Hydroxyadamantane) was used to synthesize antiallergic drug Mizolastine.</p>

Thymidine (DThyd) is a cell synchronizing agent and a precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis. Cost-effective and quality-assured.

<p>N-Methylnuciferine is an alkaloid from Lotus Plumule that ameliorates lipopolysaccharide-induced depression-like behavior.</p>

anticancer

Aristolone (Aristofone) has potential anti-cancer activity.

<p>Angelic anhydride, a (Z)-2-Methylbut-2-enoic anhydride derivative, helps synthesize pain-relief agents in butterbur.</p>

Incensole boosts β-cells and insulin secretion, raising body weight and liver glycogen in rats.