CAS: 1009298-09-2 - (5-{2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl}-2-methoxyphenyl)methanol

Fórmula: C₂₅H₃₁N₅O₄

InChI: InChI=1S/C25H31N5O4/c1-16-14-33-10-8-29(16)24-20-5-6-21(18-4-7-22(32-3)19(12-18)13-31)26-23(20)27-25(28-24)30-9-11-34-15-17(30)2/h4-7,12,16-17,31H,8-11,13-15H2,1-3H3/t16-,17-/m0/s1

Chave InChI: InChIKey=KVLFRAWTRWDEDF-IRXDYDNUSA-N

SMILES: OCC=1C=C(C=CC1OC)C2=NC=3N=C(N=C(C3C=C2)N4CCOCC4C)N5CCOCC5C

Sinónimos:

• 5-[2,4-Bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
• Azd 8055
• Azd8055
• Benzenemethanol, 5-[2,4-bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-
• Ccg 168
• Lm1148
• Nvp-Ccg 168
• [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxyphenyl]methanol
• [5-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[5,6-e]pyrimidin-7-yl]-2-methoxyphenyl]methanol

Benzenemethanol, 5-[2,4-bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-

CAS: 1009298-09-2

• Fórmula: C₂₅H₃₁N₅O₄
• Pureza: 95%
• Cor e Forma: Solid
• Peso molecular: 465.5447

AZD-8055

CAS: 1009298-09-2

• Pureza: ≥ 95.0%
• Cor e Forma: Yellow powder or solid

AZD-8055

CAS: 1009298-09-2

AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold …

• Fórmula: C₂₅H₃₁N₅O₄
• Pureza: 97.45% - 99.69%
• Cor e Forma: Solid
• Peso molecular: 465.54

AZD8055

CAS: 1009298-09-2

Applications A potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of …

• Fórmula: C₂₅H₃₁N₅O₄
• Cor e Forma: Neat
• Peso molecular: 465.54

AZD 8055

CAS: 1009298-09-2

A selective and ATP-competitive inhibitor of mTOR kinase with an IC50 value of 0.8 nM. …

• Fórmula: C₂₅H₃₁N₅O₄
• Pureza: Min. 95%
• Peso molecular: 465.54 g/mol