CAS 100986-89-8

Ácido Q de levofloxacina

Descrição:

Ácido Q de levofloxacina, com o número CAS 100986-89-8, é um composto químico que é um derivado da levofloxacina, que é um antibiótico fluoroquinolona. Esta substância é caracterizada pela sua capacidade de inibir a girase do DNA bacteriano e a topoisomerase IV, enzimas críticas para a replicação e transcrição do DNA bacteriano. Ácido Q de levofloxacina é tipicamente um pó cristalino branco a off-white, solúvel em água e vários solventes orgânicos, o que facilita seu uso em formulações farmacêuticas. Sua estrutura molecular inclui um núcleo bicíclico com um átomo de flúor, contribuindo para sua atividade antibacteriana de amplo espectro contra bactérias Gram-positivas e Gram-negativas. O composto é frequentemente utilizado no tratamento de infecções do trato respiratório, infecções do trato urinário e infecções de pele. Além disso, pode apresentar algum grau de fototoxicidade e possui requisitos específicos de armazenamento para manter sua estabilidade. Assim como outras fluoroquinolonas, é essencial monitorar os potenciais efeitos colaterais, incluindo tendinite e efeitos no sistema nervoso central.

Fórmula: C₁₉H₂₀FN₃O₆

InChI: InChI=1/C13H9F2NO4/c1-5-4-20-12-9(15)8(14)2-6-10(12)16(5)3-7(11(6)17)13(18)19/h2-3,5H,4H2,1H3,(H,18,19)/t5-/m0/s1

Chave InChI: InChIKey=NVKWWNNJFKZNJO-YFKPBYRVSA-N

SMILES: O=C1C=2C=3N(C=C1C(O)=O)[C@@H](C)COC3C(F)=C(F)C2

Sinónimos:

• (3S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• (3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• (S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
• (S)-9,10-Difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-
• 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, (S)-
• 9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-(3S)-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• 9,10-Difluoro-3-(S)-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid
• 9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
• Levofloxacin Q-acid
• Levofloxacin acid
• Levofluorocarboxylic acid
• Levofloxacin carboxylic acid
• 9,10-DIFLUORO-2,3-DIHYDRO-3-(S)-METHYL-7-OXO-7H-PY
• 8,9-difluoro-3-methyl-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid
• S(-)-9,10-DIFL-2,3-DIHYDRO-3-ME-7H-PYRI&
• (-)-9,10-DIFLUORO-3(S)-METHL-7-OXO-2,3-DIHYDRO-7H-PRYIDO[1,2,3-DE]1,2-BENZOX-AZINE-6-CARBOXYLICACID

Levofloxacin Q-Acid

CAS: 100986-89-8

Fórmula: C₁₃H₉F₂NO₄

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 281.21

Ref: 3B-L0238

LEVOFLOXACIN IMPURITY F CRS

CAS: 100986-89-8

LEVOFLOXACIN IMPURITY F CRS

Ref: 41-Y0002084

Levofloxacin Related Compound B ((S)-9,10,difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid)

CAS: 100986-89-8

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Fórmula: C₁₃H₉F₂NO₄

Cor e Forma: White Off-White Crystalline Powder

Peso molecular: 281.04996

Ref: 45-1362125

7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, (3S)-

CAS: 100986-89-8

Fórmula: C₁₃H₉F₂NO₄

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 281.2117

Ref: IN-DA0003DO

Levofloxacin carboxylic acid

CAS: 100986-89-8

Levofloxacin carboxylic acid

Pureza: 98%

Peso molecular: 281.21g/mol

Ref: 54-PC109150

Levofloxacin EP Impurity F (Levofloxacin USP Related Compound B)

CAS: 100986-89-8

Fórmula: C₁₃H₉F₂NO₄

Cor e Forma: Off-White Solid

Peso molecular: 281.21

Ref: 4Z-L-232

(S)-9,10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid

CAS: 100986-89-8

Cor e Forma: Neat

Ref: 86-MM0846.01

(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid

CAS: 100986-89-8

(S)-(-)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid is a fluoroquinolone compound used in biochemical experiments and drug synthesis research.

Fórmula: C₁₃H₉F₂NO₄

Pureza: 99.10%

Cor e Forma: Solid

Peso molecular: 281.21

Ref: TM-T65424

Levofloxacin EP Impurity F

CAS: 100986-89-8

Fórmula: C₁₃H₉F₂NO₄

Peso molecular: 281.21

Ref: ST-EA-CP-L17006

Levofloxacin Carboxylic Acid (Levofloxacin Difluoro Impurity)

Produto Controlado

CAS: 100986-89-8

Impurity Levofloxacin USP Related Compound B
Applications Levofloxacin intermediate.
References Liu, Bo; Y., et al.: Bioorg. Med. Chem., 13, 2451 (2005), Lalitha D., et al.: J. Pharm. Biomed. Anal., 50, 710 (2009),

Fórmula: C₁₃H₉F₂NO₄

Cor e Forma: Neat

Peso molecular: 281.21

Ref: TR-L360250

(S)-9,10-Difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

CAS: 100986-89-8

Fórmula: C₁₃H₉F₂NO₄

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 281.215

Ref: 10-F222352

Levofloxacin carboxylic acid

CAS: 100986-89-8

Levofloxacin is a synthetic molecule with an asymmetric carbon atom in its heterocycle. It is synthesized by reacting chloroform with 2-fluoro-5-nitrobenzaldehyde, which reacts further with sodium hydroxide and hydrochloric acid to form the levofloxacin carboxylic acid. Impurities can be found in the reaction product due to chlorine atoms that are formed during the synthesis. The amount of impurities present in the final product can be determined using a titration method or through HPLC analysis. Levofloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.

Fórmula: C₁₃H₉F₂NO₄

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 281.21 g/mol

Ref: 3D-IL24882